At about 1746 central time, a Piper PA-46-350P apparently crashed while on approach to General Dewitt Spain Airport. The two occupants are missing and presumed dead and the wreckage is believed to be submerged in the Mississippi River. Radar data showed the airplane flying a GPS approach to runway 16 but zig-zagging across the final approach course. It appeared to turn as depicted on the approach plate for a missed approach about a half-mile from the threshold, but then it dropped off radar at a point that corresponds to the river.