The airplane was destroyed when it collided with trees during an instrument approach at 0841 Eastern time, fatally injuring the Private pilot and passenger. Instrument conditions prevailed. After being cleared for the GPS Runway 5 approach and approximately four miles from the airport inside the final approach fix, the pilot reported a missed approach, made a left turn and began a descent to 1400 feet. Control tower personnel asked the pilot if he had the airport in sight, to which he responded “negative.” The airplane continued to descend until it was lost from radar.